R Aparanjitha1* , GM Imran2 , Kinjal Mondal3
1JNTU College of Pharmaceutical Sciences, Telangana 502110, India.
2Department of Agronomy, Prof. Jayashankar Telangana State Agricultural University, Hyderabad, Telangana 500030, India.
3Department of Molecular Biology and Biotechnology, Maharana Pratap University of Agriculture and Technology, Udaipur -313001 (Raj.), India.
Corresponding Author Email: aparanjitharajpur@gmail.com
DOI : https://doi.org/10.51470/AGRI.2023.2.3.06
Abstract
Nanofertilizers, a cutting-edge advancement in agricultural technology, have garnered considerable attention for their potential to revolutionize crop production and promote sustainable farming practices. This paper provides a comprehensive overview of nanofertilizers, focusing on their design, properties, applications, and environmental implications. By encapsulating nutrients within nano-sized carriers, nano fertilizers offer controlled release mechanisms that optimize nutrient delivery to plants while minimizing environmental impact. The unique properties of nanofertilizers, including their small size and high surface area-to-volume ratio, facilitate enhanced nutrient absorption and utilization by crops. Moreover, nano fertilizers can be tailored to respond to specific environmental cues, further enhancing their efficacy in diverse agroecosystems. However, the widespread adoption of nano fertilizers raises concerns regarding their potential risks and unintended consequences, necessitating careful evaluation of their environmental fate and toxicity. Through a balanced assessment of opportunities and challenges, this paper underscores the transformative potential of nanofertilizers in promoting sustainable crop growth and advancing global food security goals.
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Introduction
The field of agriculture is undergoing a significant transformation driven by technological innovations aimed at enhancing productivity, sustainability, and resilience in food production systems. Among these innovations, nanotechnology has emerged as a promising frontier, offering novel solutions to address longstanding challenges in agriculture [1-2]. Nanofertilizers, characterized by their nano-sized particles and tailored nutrient delivery mechanisms, represent a breakthrough in nutrient management practices with the potential to revolutionize crop production. Traditional fertilizers, while essential for ensuring adequate nutrient supply to plants, often suffer from inefficiencies associated with nutrient losses through leaching, volatilization, and chemical reactions in the soil. These losses not only diminish the effectiveness of fertilizers but also contribute to environmental pollution, soil degradation, and eutrophication of water bodies [3-4], nanofertilizers offer a paradigm shift by delivering nutrients in a controlled and targeted manner, thereby optimizing nutrient uptake by plants while minimizing adverse environmental impacts. The design and development of nanofertilizers leverage the unique properties of nanomaterials, including their small size, high surface area-to-volume ratio, and tunable surface chemistry [5]. By encapsulating nutrients within nano-sized carriers, such as nanoparticles, nanocapsules, or nanotubes, nanofertilizers enable precise control over nutrient release kinetics, solubility, and availability to plants. Surface modifications and functionalization further enhance the stability, dispersibility, and biocompatibility of nanofertilizers, allowing for tailored nutrient delivery to specific plant tissues and root zones. The applications of nanofertilizers extend across a wide range of crops, soil types, and agroecosystems, offering opportunities to improve nutrient use efficiency, enhance crop yields, and mitigate environmental impacts [6-7]. Through targeted nutrient delivery, nanofertilizers reduce the need for excessive fertilizer application, thus conserving resources and reducing production costs for farmers. Moreover, the controlled release properties of nanofertilizers ensure sustained nutrient availability to plants throughout the growing season, minimizing nutrient wastage and maximizing crop productivity. However, alongside the promising benefits, the widespread adoption of nanofertilizers also raises important considerations regarding their environmental fate, safety, and regulatory oversight [8-9]. The potential risks associated with nanomaterials, including nanoparticle toxicity, bioaccumulation, and ecotoxicological effects, underscore the need for comprehensive risk assessments and regulatory frameworks to ensure the safe and responsible use of nanofertilizers in agriculture. In this context, this review aims to provide a comprehensive overview of nanofertilizers, encompassing their design principles, applications, environmental implications, and future prospects. By critically evaluating the opportunities and challenges associated with nanofertilizers, this review seeks to inform stakeholders, researchers, policymakers, and practitioners about the transformative potential of nanotechnology in advancing sustainable agriculture and global food security goals [10-11]. Through interdisciplinary collaborations and evidence-based approaches, we can harness the power of nanofertilizers to create resilient, resource-efficient, and environmentally sustainable food production systems for the benefit of present and future generations.
Figure 1. Applications of Nanotechnology in Agriculture. Nanotechnology holds significant promise for revolutionizing agriculture, offering innovative solutions to enhance various aspects of crop production and management. The diagram illustrates several key applications of nanotechnology in agriculture, highlighting their potential contributions to improving crop growth, yield, and productivity [21, 22, 23, 24, 25, 26, 27], and copyright permission from MDPI.
1. Controlled Release Nanofertilizers: Nanofertilizers with controlled release mechanisms offer precise nutrient delivery to plants, optimizing nutrient uptake and utilization. This results in improved crop growth, enhanced yields, and increased productivity.
2. Nano-based Target Delivery (Gene Transfer): Nano-based target delivery systems facilitate gene transfer and crop improvement, allowing for the precise delivery of genetic material to plant cells. This technology holds promise for developing genetically modified crops with desirable traits.
3. Nanopesticides for Efficient Crop Protection: Nanopesticides exhibit enhanced efficacy and targeted action against pests and pathogens, offering efficient crop protection while minimizing environmental impact and reducing chemical residues.
4. Nanosensors and Computerized Controls: The integration of nanosensors and computerized controls enables precision farming practices, allowing farmers to monitor and manage crop growth conditions, soil parameters, and environmental factors with high precision and accuracy.
5. Promotion of Plant Stress Tolerance and Soil Enhancement: Nanomaterials can be utilized to promote plant stress tolerance, mitigate abiotic and biotic stresses, and enhance soil fertility and structure. This contributes to improved crop resilience and sustainable soil management practices.
Nanofertilizer Design and Properties:
Nanofertilizers are engineered with precision to optimize nutrient delivery to plants while minimizing losses and maximizing efficiency. The design process involves the selection of appropriate nanomaterials and the incorporation of nutrients into nano-sized carriers, allowing for controlled release and targeted delivery mechanisms [12].
1. Nano-sized particles: Nanofertilizers are characterized by their ultra-small particle size, typically ranging from 1 to 100 nanometers. This nano-scale dimension offers several advantages, including increased surface area-to-volume ratio, enhanced reactivity, and improved dispersibility in aqueous solutions. The small size of nanofertilizer particles facilitates their penetration into plant tissues and root systems, promoting efficient nutrient uptake and utilization by crops [13].
2. Tailored nutrient release: One of the hallmark features of nanofertilizers is their ability to release nutrients in a controlled and sustained manner. By encapsulating nutrients within nano-sized carriers, such as nanoparticles or nanocapsules, nanofertilizers can modulate the release kinetics and duration of nutrient availability to plants. This controlled release mechanism helps to synchronize nutrient supply with plant demand, minimizing nutrient wastage and maximizing crop uptake efficiency [14].
3. Surface modification and functionalization: Nanofertilizers can be surface-modified or functionalized to enhance their stability, dispersibility, and targeting capabilities. Surface modifications, such as coating with biocompatible polymers or ligands, improve the compatibility of nanofertilizers with soil particles and enhance their interaction with plant roots. Functionalization enables the attachment of specific molecules or ligands that facilitate targeted delivery of nutrients to specific plant tissues or cellular compartments, further enhancing nutrient uptake and utilization efficiency [15].
4. Enhanced nutrient stability: Nanofertilizers offer improved stability and solubility of nutrients, protecting them from degradation, leaching, and volatilization in the soil environment. The encapsulation of nutrients within nano-sized carriers helps to shield them from environmental stresses, such as pH fluctuations, microbial activity, and adverse weather conditions. This enhanced stability ensures prolonged nutrient availability in the rhizosphere, promoting sustained plant growth and development over the entire cropping cycle [16].
5. Environmental compatibility: Despite their small size and high reactivity, nanofertilizers are designed to minimize adverse environmental impacts and ecological risks. Biodegradable nanomaterials and eco-friendly synthesis methods are employed to reduce the environmental footprint of nanofertilizer production and application. Furthermore, the controlled release properties of nanofertilizers help to mitigate nutrient runoff, soil erosion, and groundwater contamination, contributing to overall environmental sustainability in agriculture, the design and properties of nanofertilizers offer unique advantages for optimizing nutrient management and promoting sustainable crop production systems. Through precise control over nutrient release, enhanced stability, and targeted delivery mechanisms, nanofertilizers have the potential to revolutionize agricultural practices and address global food security challenges in an environmentally responsible manner. Continued research and development efforts are needed to further advance the design and application of nanofertilizers, ensuring their safe and effective integration into modern farming practices [17].
Applications and Benefits
Nano-fertilizers offer multifaceted benefits to agricultural systems, including enhanced nutrient uptake, improved crop yields, and reduced environmental pollution. By delivering nutrients in a controlled and targeted manner, nano fertilizers minimize nutrient losses and optimize nutrient use efficiency, thereby reducing the need for excessive fertilizer application [18]. This not only improves resource efficiency but also mitigates the adverse effects of nutrient runoff on soil and water quality. Furthermore, nanofertilizers can be tailored to release nutrients in response to specific environmental stimuli, such as soil moisture levels or plant demand, further enhancing their effectiveness in diverse agroecosystems.
Environmental Considerations
While nanofertilizers hold great promise for sustainable agriculture, their widespread adoption raises concerns regarding potential environmental risks and unintended consequences. The fate and behavior of nanofertilizers in soil and water ecosystems, as well as their long-term impacts on soil health and microbial communities, warrant careful evaluation. Additionally, the synthesis and disposal of nanomaterials may pose challenges in terms of energy consumption, waste generation, and nanoparticle toxicity [19-20]. Addressing these concerns requires a holistic approach that integrates scientific research, regulatory oversight, and stakeholder engagement to ensure the safe and responsible use of nanofertilizers in agriculture.
Conclusion
Nanofertilizers represent a ground breaking innovation with the potential to transform agricultural practices and address pressing challenges related to food security, resource sustainability, and environmental stewardship. Through meticulous design and engineering, nanofertilizers offer precise control over nutrient delivery, enhanced plant uptake efficiency, and reduced environmental impact compared to conventional fertilizers. The widespread adoption of nanofertilizers holds promise for enhancing crop yields, improving nutrient use efficiency, and minimizing nutrient losses in agricultural systems. By delivering nutrients in a controlled and targeted manner, nanofertilizers help to optimize plant nutrition, promote balanced crop growth, and mitigate the adverse effects of nutrient runoff on soil and water quality. Furthermore, nanofertilizers offer opportunities to tailor nutrient release kinetics, respond to specific environmental cues, and target nutrient delivery to specific plant tissues or root zones. These capabilities enable farmers to optimize fertilizer applications, reduce production costs, and improve overall agricultural productivity while minimizing environmental degradation. However, the integration of nanofertilizers into agricultural systems also raises important considerations regarding their environmental fate, safety, and regulatory oversight. Comprehensive risk assessments, environmental monitoring, and regulatory frameworks are essential to ensure the safe and responsible use of nanofertilizers in agriculture, minimizing potential risks to human health, ecosystems, and the environment, nano fertilizers offer a promising pathway towards achieving sustainable agriculture, resilient food systems, and a healthier planet. By leveraging the transformative potential of nanotechnology, we can unlock new opportunities to feed a growing population, conserve natural resources, and safeguard the environment for future generations. With thoughtful stewardship and responsible innovation, nano fertilizers can play a pivotal role in shaping the future of agriculture and ensuring food security for all.
References
1. Khan, M. I., Khan, S. A., & Islam, T. (2019). Nanofertilizers: A potential approach for enhancing nutrient use efficiency in crop plants. In Nanotechnology: Advances and Real-Life Applications (pp. 237-258). IntechOpen.
2. DeRosa, M. C., Monreal, C., Schnitzer, M., & Walsh, R. (2010). Nanotechnology in fertilizers. Nature Nanotechnology, 5(2), 91-91.
3. Liu, R., Lal, R., & Potdar, M. K. (2015). Effects of nanofertilizer on soil nutrient concentration and enzyme activities. Annals of Environmental Science, 9, 13-18.
4. Dimkpa, C. O., McLean, J. E., Latta, D. E., Manangón, E., Britt, D. W., Johnson, W. P., & Boyanov, M. I. (2013). CuO and ZnO nanoparticles: phytotoxicity, metal speciation, and induction of oxidative stress in sand-grown wheat. Journal of Nanoparticle Research, 15(8), 1896.
5. Jiménez-Lamana, J., Laborda, F., Bolea, E., Abad-Álvaro, I., Castillo, J. R., & Abadía, J. (2017). Characterization of metal–metal and metal–ligand interactions in metal-exposed plants by X-ray spectrometry techniques. Trends in Analytical Chemistry, 90, 85-96.
6. Gogos, A., Knauer, K., & Bucheli, T. D. (2012). Nanomaterials in plant protection and fertilization: current state, foreseen applications, and research priorities. Journal of Agricultural and Food Chemistry, 60(39), 9781-9792.
7. Geisler-Lee, J., Wang, Q., Yao, Y., Zhang, W., Geisler, M., Li, K., & Huang, Y. (2013). Phytotoxicity, accumulation and transport of silver nanoparticles by Arabidopsis thaliana. Nanotoxicology, 7(3), 323-337.
8. Ze, Y., Sheng, L., Zhao, X., Hong, J., Ze, X., Yu, X., & Liu, D. (2010). Analysis of the toxic potential of silver nanoparticles on the reproductive system of adult male rats. Biomaterials, 31(31), 8065-8073.
9. He, L., Liu, Y., Mustapha, A., & Lin, M. (2011). Antifungal activity of zinc oxide nanoparticles against Botrytis cinerea and Penicillium expansum. Microbiological Research, 166(3), 207-215.
10. Kah, M., Tufenkji, N., & White, J. C. (2019). Nano-enabled strategies to enhance crop nutrition and protection. Nature Nanotechnology, 14(6), 532-540.
11. Raliya, R., & Tarafdar, J. C. (2013). ZnO nanoparticle biosynthesis and its effect on phosphorous-mobilizing enzyme secretion and gum contents in clusterbean (Cyamopsis tetragonoloba L.). Agriculture, Ecosystems & Environment, 181, 120-128.
12. Priester, J. H., Ge, Y., Mielke, R. E., Horst, A. M., Moritz, S. C., Espinosa, K., … & Holden, P. A. (2012). Soybean susceptibility to manufactured nanomaterials with evidence for food quality and soil fertility interruption. Proceedings of the National Academy of Sciences, 109(37), E2451-E2456.
13. Zheng, L., Hong, F., Lu, S., Liu, C., & Effect of nano-TiO2 on strength of naturally aged seeds and growth of spinach. Biological Trace Element Research, 104(1), 83-91.
14. Thuesombat, P., Hannongbua, S., & Akasit, S. (2014). Chadchawan, S. Effect of Silver Nanoparticles on Rice (Oryza sativa L. cv. KDML 105) Seed Germination and Seedling Growth. Ecotoxicology and Environmental Safety, 104, 302-309.
15. Lin, D., & Xing, B. (2007). Phytotoxicity of nanoparticles: inhibition of seed germination and root growth. Environmental Pollution, 150(2), 243-250.
16. Lee, W. M., An, Y. J., & Yoon, H. (2008). Kweon, J. H. Toxicity and bioavailability of copper nanoparticles to the terrestrial plants mung bean (Phaseolus radiatus) and wheat (Triticum aestivum): plant agar test for water-insoluble nanoparticles. Environmental Toxicology & Chemistry, 27(9), 1915-1921.
17. Wang, Z., Xie, X., Zhao, J., Liu, X., Feng, W., & White, J. C. (2012). Xing, B. Xylem- and phloem-based transport of CuO nanoparticles in maize (Zea mays L.). Environmental Science & Technology, 46(8), 4434-4441.
18. Ma, X., Geiser-Lee, J., Deng, Y., Kolmakov, A., & Interactions between engineered nanoparticles (ENPs) and plants: phytotoxicity, uptake and accumulation. Science of the Total Environment, 408(16), 3053-3061.
19. Dimkpa, C. O., McLean, J. E., Britt, D. W., Anderson, A. J., & Antifungal activity of ZnO nanoparticles and their interactive effect with a biocontrol bacterium on growth antagonism of the plant pathogen Fusarium graminearum. Biometals, 25(1), 45-56.
20. Ditta, A. (2019). Emerging nano-fertilizer technologies for agriculture. Springer
Worrall, E.; Hamid, A.; Mody, K.; Mitter, N.; Pappu, H. Nanotechnology for plant disease management. Agronomy 2018, 8, 285.Verma, S.K.; Das, A.K.; Patel, M.K.; Shah, A.; Kumar, V.; Gantait, S. Engineered nanomaterials for plant growth and development: A perspective analysis. Sci. Total Environ. 2018, 630, 1413–1435.
Zaytseva, O.; Neumann, G. Carbon nanomaterials: Production, impact on plant development, agricultural and environmental applications. Chem. Biol. Technol. Agric. 2016, 3, 17. [
Ghormade, V.; Deshpande, M.V.; Paknikar, K.M. Perspectives for nano-biotechnology enabled protection and nutrition of plants. Biotechnol. Adv. 2011, 29, 792–803.
Loh, X.J.; Lee, T.-C.; Dou, Q.; Deen, G.R. Utilising inorganic nanocarriers for gene delivery. Biomater. Sci. 2016, 4, 70–86.
Kumar, S.; Nehra, M.; Dilbaghi, N.; Marrazza, G.; Hassan, A.A.; Kim, K.-H. Nano-based smart pesticide formulations: Emerging opportunities for agriculture. J. Control. Release 2018, 294, 131–153.
McShane, H.V.; Sunahara, G.I. Environmental perspectives. In Nanoengineering; Elsevier: Amsterdam, The Netherlands, 2015; pp. 257–283.