The present study is carried out to detect the phytochemicals of five diverse varieties of sorghum millet from Telangana state. Sorghum or jowar is an enriched source of different phytochemicals, like glycosides, saponins, flavonoids, and alkaloids. Sorghum consumption reduces the risk of the certain types of cancer in humans.  India ranks fifth in the production of Sorghum among the countries of the world.  Sorghum is packed with calcium, iron, potassium, phosphorous, protein, fiber, and good antioxidants that contain B vitamins like thiamin and riboflavin. Phytochemicals in sorghum and millets have become a critical area of research. Phytochemical analysis was performed and the result revealed the presence of steroids, Glycosides, Volatile oils, saponins, Tannins, and Flavonoids in all five varieties of Sorghum. GC-MS analysis also revealed the presence of six major bioactive compounds in almost all the genotypes studied.